I started taking duromine 30mg several weeks ago and it worked instantly. I had minimal appetite but the side effects were quite intense. After two weeks I decided to take a few days off, just for a break. When I resumed taking the duromine NOTHING happened. No change in appetite, no sign I was even taking the medication. A week later I still feel the same, I've no idea what happened? Has anyone else taken a break from duromine and then found upon taking it again it has stopped working? Is there anything I can do?