Duromine Dosing And Overdosing

​Inside you find two blisters, each of which contains 15 capsules of Duromine 15 mg, and capsules that contain 15 mg of the active ingredient Phentermine are of green and grey color and contain the inscription Duromine 15 on both the body and cap of the capsule. They look like this:

Duromine 30 mg

When you buy a one-month stock of Duromine 30 mg by INova Pharmaceuticals, your package looks like this:

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Inside you find two blisters, each of which contains 15 capsules of Duromine 30 mg, and capsules that contain 30 mg of the active ingredient Phentermine are of grey and reddish brown color and contain the inscription Duromine 30 on both the body and cap of the capsule. They look like this:

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Duromine 40 mg

When you buy a one-month stock of Duromine 40 mg (Australia and Hong Kong only) by INova Pharmaceuticals, your package looks like this:

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Inside you find two blisters, each of which contains 15 capsules of Duromine 40 mg, and capsules that contain 40 mg of the active ingredient Phentermine are of grey and orange color and contain the inscription Duromine 40 on both the body and cap of the capsule. They look like this:

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Each capsule contains a certain amount of the active substance mixed with excipients that provide a proper rate of the drug absorption. The film coating of the capsule that you see also plays an important role in the way that your body receives Duromine.

Both the film coating and the excipients inside a Duromine capsule are responsible for the gradual release of the active substance. Therefore, it is strongly recommended not to crush or chew the capsules. Otherwise, you may interfere with the intended drug release and cause irritation of your esophagus.

Which Duromine dose should I use?

According to the recommendations from the drug manufacturer, doctors should prescribe the medium Duromine dose of 30 mg to obese people, who are beginning their first Duromine course. This implies that, depending on the action of the anorectic and the Duromine side effects that manifest, this dose can be either lowered to 15 mg or increased to 40 mg (where available).

However, a portion of doctors that are slightly hesitant to put their overweight patients on Duromine, prefer prescribing the 15 mg dose to let their body slowly adapt to the strong effect of the anorectic. If the dose of 15 mg proves insufficient, patients can be prescribed the 30 mg dose. If it also proves insufficiently strong, or patient becomes “immune to Duromine”, the dose can be increased to 40 mg.

There are multiple cases, when 15 mg is strong enough during the entire 3-month course of Duromine and people do not up it. At times, those who consider the effect of 15 mg dosage to be fading, begin taking 30 mg Duromine, yet find the side effects too strong and switch back to 15 mg. The same works with switching from 30 mg to 40 mg Duromine capsules.

At that, many people begin their journey with the highest Duromine dose of 40 mg and find it effective in terms of both appetite suppression and side effects.

As you can see, Duromine dosage is a very individual thing, and it is extremely important to follow your doctor’s recommendations and never double Duromine dose, even if you think that the effect is too low. Discuss the issue with your doctor instead of posing yourself to a threat of stronger side effects.

How long to take

The recommended period for Duromine use is 3 months. Do not extend the anti-obesity program that implies the use of this anorectic. If you manage to lose a considerable amount of weight while on Duromine and want to continue using it to lose more weight, take a drug holiday for 1 to 2 months, depending on your doctor’s recommendations.

Then, you can continue using Duromine to lose more weight under medical supervision and in compliance with your weight loss plan.

How much to take

No more than one Duromine capsule should be taken in a day. However, some doctors may recommend taking a second 15 mg Duromine capsule closer to the afternoon to their patients, who report weak to zero appetite suppression while using 15 mg dose. At that, Duromine doses of 30 mg and 40 mg should never be doubled.

When to take

To avoid such common side effect of Duromine, as insomnia, the capsule should be taken first thing in the morning on an empty stomach or during breakfast. Some people report better results when they take this anorectic without food, while others report nausea when trying to administer Duromine on a fasting stomach.

If your usual awakening time is 8 AM and later, it is advisable to set an alarm clock for earlier, take Duromine, and resume your sleep. Otherwise, you risk having sleep problems at night. However, each patient finds his own perfect dosing schedule, which helps him avoid sleeplessness and ensures a day-through appetite suppression.

If you miss a dose

If you remember about missing a Duromine dose before the lunch time, you can safely take it. Taking this anorectic later may result in insomnia. Do not take a double dose of Duromine to make up for the missed dose. Better skip one day, instead of overdosing, since this appetite suppressant is a potent drug and requires a strict compliance with the recommended dosing regimen.

If you or someone else took too much Duromine

Never advise or encourage any person to double his Duromine dose (nor offer your Duromine to someone else). If you are aware of the fact that someone (or you) took this medication in a dose that exceeds the recommended one, you should seek medical help by contacting a doctor or a local poison center.

Signs of overdosage with Duromine can manifest from the part of various body systems, and it is important to inform the doctor about any changes in state and behavior of the person who overdosed. If you are provided a consultation by phone, strictly follow all recommendations that you are given.

What should I do if I miss a dose of Duromine?

Unless your doctor prescribes you the lowest possible Duromine dose of 15 mg, which can sometimes be taken 2 times a day at certain intervals for a better appetite management, you should NEVER take two Duromine caps at once.

The 30 mg and 40 mg doses are strong enough to cause unpleasant side effects, and exceeding the recommended dose can lead to exacerbation of worrisome sensations and even require urgent medical assistance.

If you, accidentally or intentionally, skip one Duromine dose, you can take it as soon as you remember about it or change your mind and decide to take it. However, you should avoid taking the missed dose if:

  • You plan to take it in the second part of the day (less than 8 hours before bedtime), since it can cause sleeplessness
  • It is close to the time when you need to take the next Duromine dose, since it can result in an overdose

Duromine is not the same as the antibiotics or any other medications that require strict introduction of another dose at exact intervals (though it is recommended to observe as equal dosing intervals, as possible). If you skip a dose, all that can happen to you is lessening of the appetite suppression and lowering of the side effects intensity.

Some people decide to take Duromine every other day or every third day, as they find out that the appetite suppressing effect provided lasts longer than 24 hours. If you are considering the possibility of taking Duromine every other day, you can try it and see if it works well for you.

However, we advise you to always consult with your doctor before you make any changes in the dosing schedule.

What should I do if I take a Duromine overdose?

First thing to remember about Duromine is to NEVER SHARE this drug with any person. You can never know for sure, whether he/she is not contraindicated to use it. The dose of the drug also plays an important role. Even if the person already takes Duromine at a lower strength, it does not mean that taking a higher dose will be as safe for him as the smaller dose is.

Signs of overdose with Duromine

If you find out that someone around you or you yourself accidentally or intentionally take Duromine in a higher dose, you should be very careful and monitor the condition of the person, who increased the dose. Though it is always better to immediately apply for medical help, people may hesitate to consult with the doctor or call for help.

Still, it is important that you address to the nearest Poison Centre or go to the Emergency department at the nearest hospital, if you notice any of the following side effects:

  • Fast breathing
  • Abnormal heart rhythms
  • Low or high blood pressure
  • Circulatory insufficiency
  • Trembling
  • Exaggerated reflex
  • Agitation
  • Mental fog
  • Hallucinations
  • Aggression
  • Panic
  • Nausea and/or vomiting
  • Gastric disturbance
  • Stomachache

When overdose symptoms manifest on the part of the CNS, central stimulation is often followed by depression and fatigue.

Non-common overdose with Duromine

Besides the common way of overdosing with Duromine, i.e. taking the drug in a higher dose at a time, you also can overdose with Duromine, if its dose is too high to be excreted by your body before you take the next dose. If this is the case, your body is under long-term intoxication with the drug and can warn you about this problem through the following signs:

  • Skin rashes
  • Severe sleeplessness
  • Irascibility
  • Overactivity
  • Personality disorder
  • Psychotic disorder that is often indistinguishable from schizophrenia

This condition requires immediate medical help. Do your best to inform the doctor about the dose of the drug that you have been using and the duration of its use, as well as every symptom that you had during the course.

Treatment for overdose with Duromine

Treatment for the overdose with Duromine is of symptomatic character and usually includes:

  • Gastric lavage to clean the stomach (if the drug was taken within the last 3-4 hours)
  • Introduction of activated charcoal for further body cleansing from the drug
  • Sedation with a barbiturate or benzodiazepine to address seizures and emotional disturbance
  • Urine acidification to further increase excretion of the anorectic from the body (only in sufficient renal function)
  • Medications for hypertension, where it complicates the condition in overdose

There is insufficient data about the effectiveness of peritoneal dialysis and hemodialysis to address overdose with Duromine, so it is unreasonable to use these measures for improving the overdosed patient’s condition.

How long does a Duromine course last?

Duromine is intended for a short-time use and should not be used longer than 12 weeks to avoid possible side effects, and for the reason that positive Duromine effects usually subside by the end of month 3, while negative effects might persist even longer. Another reason for the importance of timely Duromine discontinuation is the risk of addiction development. To avoid it, you need to take a longer break between the 3-month courses.

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